GUIA DE ACTUALIZACION 2009 PARA EL TRATAMIENTO BIOLOGICO DE LA MANIA AGUDA EN EL TRASTORNO BIPOLAR.

World Journal of Biological Psychiatry
GUIDELINES

The World Federation of Societies of Biological Psychiatry (WFSBP)
Guidelines for the Biological Treatment of Bipolar Disorders: Update 2009 on the Treatment of Acute Mania

Heinz Grunze ab; Eduard Vieta c; Guy M. Goodwin d; Charles Bowden e; Rasmus W. Licht f; Hans-Jürgen Möller b; Siegfried Kasper g; WFSBP Task Force on Treatment Guidelines for Bipolar Disorders h

a Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, UK
b Department of Psychiatry, Ludwig-Maximilians-University, Munich, Germany
c Bipolar Disorders Programme, Institute of Neuroscience, Hospital Clinic, University of
Barcelona, IDIBAPS, CIBERSAM, Barcelona, Catalonia, Spain
d Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK
e Department of Psychiatry, University of Texas Health Science Center, San Antonio, TX, USA
f Mood Disorders Research Unit, Aarhus University Hospital, Risskov, Denmark
g Department of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria
h WFSBP Task Force on Treatment Guidelines for Bipolar Disorders

Abstract

These updated guidelines are based on a first edition that was published in 2003, and have been edited and updated with the available scientific evidence until end of 2008. Their purpose is to supply a systematic overview of all scientific evidence pertaining to the treatment of acute mania in adults. The data used for these guidelines have been extracted from a MEDLINE and EMBASE search, from the clinical trial database clinicaltrials.gov, from recent proceedings of key conferences, and from various national and international treatment guidelines. Their scientific rigor was categorised into six levels of evidence (A
F). As these guidelines are intended for clinical use, the scientific evidence was finally asigned different grades of recommendation to ensure practicability.

The World Journal of Biological Psychiatry, 2009; 10(2): 85-116
ISSN 1562-2975 print/ISSN 1814-1412 online
(C) 2009 Informa UK Ltd. (Informa Healthcare, Taylor & Francis AS)
DOI: 10.1080/15622970902823202

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